VMR Institute remains a leading center of excellence for the diagnosis and treatment of diseases of the vitreous, macula, and retina.

To stay at the forefront VMR continually conducts extensive basic science and clinical research.

Current Research



Dr. Sebag began conducting vitreous research as a medical student at the College of Physicians & Surgeons, Columbia University. Over the past 30 years this has been his passion and has resulted in an unparalleled expertise in this area. Considered one of the world’s pre-eminent experts in vitreous, Dr. Sebag has published widely in this area.


Pharmacologic Vitreolysis



Age-Related Macular Degeneration (AMD)


Retinal Detachment


Macular Holes and Macular Pucker


Optic Nerve


General Interest


Book Chapters


Imaging and Diagnostic Testing


Imaging of the Vitreous, Macula, & Retina

Using the newest technology for digital imaging, Dr. Sebag and Dr. Chong are supervising 4th year medical students and research fellows from USC, who are conducting research in collaboration with the Doheny Eye Institute and the New York Eye & Ear Infirmary, Harvard Medical School, and the University of Sydney in Australia. This powerful new imaging technology has been available at the VMR Institute since November of 2005 and has been used extensively in clinical care and research. The results have been presented at the American Academy of Ophthalmology, the Club Jules Gonin, the Retina Society, and the Association for Research and Vision in Ophthalmology (ARVO).



3-Dimensional Threshold Amsler Grid Testing

In collaboration with scientists at the Doheny Eye Institute and Caltech/JPL, Dr. Sebag is developing advanced diagnostic instrumentation to detect central visual field abnormalities in patients with macular degeneration, diabetic retinopathy, macular holes, macular pucker, central serous chorio-retinopathy, and retinal vein occlusions. Doheny Eye Institute medical students have been conducting studies at the VMR Institute with this new technology, and the research results have been presented at various meetings around the world. Currently, work is being directed to making this test available online so that patients will one day be able to test themselves at home.



VMR Institute7677 Center Ave. #400
Huntington Beach, CA 92647